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What component of the conduction pathway transmits the action potential to the ventricular contractile cells?


A) nodal pathways
B) SA node
C) Purkinje fibers
D) AV node
E) bundle of His

F) A) and B)
G) A) and E)

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Conduction through which of the following is slow to allow atria to contract before the ventricles?


A) AV bundle (bundle of His)
B) AV node
C) atria
D) SA node
E) Purkinje fibers

F) A) and E)
G) B) and D)

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John has aged gracefully now at the age of 75 with distinguished gray hair and beard, unfortunately his SA node has failed and his heart rate is down to 40 beats per minute. An ECG shows bradycardia and his stroke volume is calculated to be 80 mL. John is short of breath and has low blood pressure and is feeling quite unwell. John's brother Jim is 78 years old and was a triathlete for many years and still swims and bikes five days a week. Jim's resting heart rate is 50 beats per minute and he feels great. His stroke volume has been calculated to be 120 mL per beat. Calculate the cardiac output for both John and Jim and explain why Jim feels so much better than John.

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CO = SV × HR. John's CO = 80 × 40 = 3200...

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What phase of the cardiac cycle is the heart in when all four valves of the heart are closed and ventricular pressure is building, but is not yet great enough to open a valve?


A) ventricular filling
B) isovolumetric relaxation
C) isovolumetric contraction
D) ventricular ejection
E) none

F) B) and E)
G) A) and D)

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Which of the following components of an ECG represents atrial depolarization?


A) P wave
B) QRS complex
C) T wave
D) PQ interval
E) TQ segment

F) A) and B)
G) D) and E)

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The opening and closure of the atrioventricular and semilunar valves is driven by


A) differences in pressure across the valve.
B) contraction of the valve.
C) contraction of the ventricle and atria that pull the valves into place.
D) contraction and relaxation of the valve.
E) contraction of muscles attached to the valves.

F) B) and E)
G) A) and B)

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Opening of what channels is responsible for the depolarization phase of the cardiac contractile cell action potential?


A) potassium channels
B) T -type calcium channels
C) funny channels
D) L -type calcium channels
E) voltage -gated sodium channels

F) B) and E)
G) D) and E)

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Which of the following structures is poorly innervated by the parasympathetic nervous system and, therefore, an increase in parasympathetic activity has little effect on this structure?


A) atrioventricular node
B) sinoatrial node
C) ventricles
D) conduction pathway
E) Purkinje fibers

F) A) and B)
G) A) and E)

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During recording of an ECG, a depolarization that travels toward a positive lead will cause an upward deflection.

A) True
B) False

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Which component of an ECG represents ventricular depolarization?


A) P wave
B) P -R interval
C) T wave
D) Q -T interval
E) QRS complex

F) D) and E)
G) None of the above

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If damage to the AV node slowed down conduction through this tissue, what would be observed on an ECG?


A) a longer P wave
B) a larger P wave
C) an inverted T wave
D) a wider QRS complex
E) a longer PR interval

F) All of the above
G) C) and D)

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Starling curves plot________ against ________.


A) stroke volume : end -systolic volume
B) heart rate : end -systolic volume
C) stroke volume : end -diastolic volume
D) cardiac output : end -diastolic volume
E) heart rate : end -diastolic volume

F) A) and E)
G) C) and E)

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Given a constant pressure, the greater the radius of the vessel, the greater the tension on the vessel walls.

A) True
B) False

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Cardiac output is in part determined by changes in stroke volume. Identify the factors involved in the determination of stroke volume.

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Cardiac output is determined by the prod...

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What causes the sounds that one hears as the heart beats?


A) the turbulence created as the valves close
B) the turbulence created as the valves open
C) the bulk movement of blood into and out of the ventricle
D) the snapping of the valves into the open position
E) the snapping of the valves into a closed position

F) B) and E)
G) A) and B)

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Which component of an ECG represents atrial depolarization?


A) P wave
B) P -R interval
C) T wave
D) Q -T interval
E) QRS complex

F) B) and D)
G) A) and E)

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Which statement best describes why clinicians use a defibrillator?


A) The ventricles of the heart are so large that only a strong current can make them depolarize, which is needed in order for them to contract and get blood to the body.
B) The applied current opens up voltage gated calcium channels in the atria causing the heart to begin a new P wave.
C) The applied current depolarizes all the muscle cells at the same time, returning synchronous electrical activity to the heart.
D) A defibrillator takes the place of the SA node and must be applied every minute to keep the heart rate normal until it regains its strength and beats on its own.
E) The applied current repolarizes the cells of the heart, hence resetting the heart for normal rhythm.

F) B) and E)
G) C) and D)

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Prolapse involves improper alignment of the atrioventricular valve such that one or more of the cusps are pushed into the atrium by the pressure developed in the ventricle.

A) True
B) False

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The preload is approximately the same as the________pressure.


A) aortic systolic
B) end -diastolic
C) atrial
D) end -systolic
E) aortic diastolic

F) C) and D)
G) A) and D)

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When blood moves through the body it travels in a circular pattern. The general pattern of blood flow follows which sequence of vessels as it leaves the heart?


A) arterioles, arteries, capillaries, venules, veins
B) veins, venules, capillaries, arterioles, arteries
C) arteries, veins, venules, arterioles, capillaries
D) veins, capillaries, venules, arterioles, arteries
E) arteries, arterioles, capillaries, venules, veins

F) A) and B)
G) B) and E)

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