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Which of the following is a source of water input?


A) digestive tract only
B) renal tubules only
C) metabolism only
D) both digestive tract and metabolism
E) both the digestive tract and renal tubules

F) A) and E)
G) C) and D)

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Which of the following is an effect of aldosterone on principal cells?


A) decreased number of Na+/K+ pumps in the basolateral membrane
B) decreased number of open Na+/K+ channels in the basolateral membrane
C) increased number of Na+/K+ pumps in the apical membrane
D) increased number of open Na+/K+ channels in the basolateral membrane
E) increased number of open Na+/K+ channels in the apical membrane

F) A) and E)
G) D) and E)

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Acidosis results in potassium retention, whereas alkalosis results in potassium depletion.

A) True
B) False

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What hormone decreases calcium levels in blood?


A) ADH
B) parathyroid hormone
C) calcitonin
D) angiotensin II
E) aldosterone

F) A) and D)
G) All of the above

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As the body becomes dehydrated, the osmolarity of the body fluids decreases.

A) True
B) False

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The hydrogen ion concentration or pH of arterial blood is regulated by the combined actions of the________and________ .


A) kidneys : buffer systems
B) lungs: buffer systems
C) kidneys : cardiovascular system
D) kidneys : lymphatic system
E) lungs : kidneys

F) A) and E)
G) None of the above

Correct Answer

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Plasma can gain solutes and/or water from which of the following?


A) gastrointestinal tract only
B) renal tubules only
C) bone only
D) both the gastrointestinal tract and bone
E) both the gastrointestinal tract and renal tubules

F) C) and D)
G) A) and C)

Correct Answer

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Aldosterone is released from the________ in response to________ _.


A) pancreas : increases in plasma glucose
B) adrenal cortex : increases in plasma potassium
C) adrenal medulla : decreases in plasma sodium
D) posterior pituitary : increases in plasma osmolarity
E) macula densa : increased flow of tubular fluid in the distal tubule

F) A) and E)
G) None of the above

Correct Answer

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What enzyme converts angiotensinogen into angiotensin I?


A) atrial natriuretic peptide
B) angiotensin converting enzyme (ACE)
C) renin
D) mucin
E) carbonic anhydrase

F) A) and C)
G) C) and D)

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Bicarbonate crosses the apical membrane of the proximal tubule by


A) HCO3 -/Cl -countertransporters.
B) conversion to carbon dioxide.
C) HCO3 -active transporters.
D) Na+/HCO3 -cotransporters.
E) Na+/HCO3 - countertransporters.

F) B) and E)
G) A) and D)

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The hemorrhage -induced decrease in blood flow to the kidneys will


A) increase the production of erythrocytes.
B) decrease the release of renin.
C) increase glomerular filtration rate.
D) increase the production of leukocytes.
E) increase the release of atrial natriuretic peptide.

F) C) and D)
G) A) and E)

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Calcium homeostasis is regulated through the digestive tract.

A) True
B) False

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The last step to synthesis of 1,25 -dihydroxy vitamin D3 occurs in what organ?


A) brain
B) liver
C) gastrointestinal tract
D) kidney
E) skin

F) B) and E)
G) A) and B)

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Angiotensinogen is synthesized by what organ?


A) pituitary gland
B) liver
C) kidney
D) bone marrow
E) adrenal gland

F) B) and D)
G) None of the above

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The effects of antidiuretic hormone (ADH) are not restricted to regulating water movement; it also affects sodium reabsorption by


A) increasing the synthesis of Na+/K+ pumps in principal cells.
B) increasing the synthesis of sodium channels in intercalated cells.
C) decreasing the synthesis of sodium channels in intercalated cells.
D) increasing the synthesis of sodium channels in principal cells.
E) decreasing the synthesis of sodium channels in principal cells.

F) A) and D)
G) B) and C)

Correct Answer

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