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Multiple Choice
A) The B cell would switch again to IgG3.
B) The B cell would remain in the germinal center but would not differentiate into a plasma cell.
C) The B cell would die by apoptosis.
D) The IgE produced would have low affinity for antigen.
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Multiple Choice
A) T-independent antigens
B) superantigens
C) subunit vaccines
D) attenuated vaccines
E) allergens.
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Multiple Choice
A) cathepsin G
B) CR2
C) eotaxin
D) major basic protein
E) ADAM10.
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Multiple Choice
A) chemotaxis of neutrophils,eosinophils,and effector T cells
B) growth factor secretion
C) smooth muscle contraction
D) connective tissue remodeling
E) All of the above are mediated by mast cells.
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Multiple Choice
A) IgG4:IgE
B) IgE:IgM
C) IgA:IgM
D) IgG1:IgG4
E) IgE:IgG4.
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Multiple Choice
A) TNF-α: immediate release from mast cells
B) mucosal mast cell production: T-cell immunodeficiencies
C) connective tissue mast cells: chymotryptase
D) lipid mediator: prostaglandins
E) leukotrienes: increase vascular permeability.
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Multiple Choice
A) cyclooxygenase
B) carboxypeptidase
C) metalloprotease
D) lipooxygenase
E) peroxidase.
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Multiple Choice
A) subcutaneous injection of epinephrine
B) intravenous injection of corticosteroids
C) intravenous injection of antihistamine
D) intravenous injection of antibiotics
E) intravenous injection of a nonsteroidal anti-inflammatory drug.
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Multiple Choice
A) ADAM10
B) experimental anti-IgE
C) aspirin (acetyl salicylate)
D) chymotryptase
E) ADAM33.
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Matching
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Multiple Choice
A) It is expressed on the surface of mast cells and basophils.
B) It is a low-affinity receptor involved in type I hypersensitivity reactions.
C) It binds to IgE in the absence of antigen.
D) It is a membrane-bound tetramer.
E) It contains signaling components that re activated following antigen cross-linking.
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Multiple Choice
A) smooth muscle contraction
B) immune complex deposition on blood vessels
C) loss of blood pressure
D) constriction of airways
E) complement activation.
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