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Several days after an initial contact with an antigen,antibody blood levels increases.This is a


A) primer response.
B) primary response.
C) precipitating response.
D) principle response.
E) cascade response.

F) A) and B)
G) D) and E)

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The process of eliminating those lymphocytes that react or respond against self-antigens is called


A) phagocytosis.
B) inflammation.
C) negative selection.
D) activation of complement.
E) natural selection.

F) A) and B)
G) C) and E)

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Cell-mediated immunity would be least effective against


A) tumor cells.
B) virally infected cells.
C) intracellular bacteria.
D) extracellular antigens.
E) intracellular parasites.

F) A) and B)
G) All of the above

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In immunodeficiency diseases,


A) the immune system fails to distinguish between self-antigens and foreign antigens.
B) inadequate B and/or T cell formation may occur.
C) IgE mediates a localized reaction.
D) serum sickness results.
E) immune surveillance occurs.

F) A) and C)
G) B) and D)

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The key signs of inflammation include all of the following EXCEPT


A) jaundice.
B) pain.
C) swelling.
D) redness.
E) heat.

F) A) and D)
G) C) and D)

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Match the type of cell with its function. -monocyte


A) first cell to enter infected tissue
B) will become macrophage in tissue
C) lyses tumor and virus-infected cells
D) cell that increases in number during a parasitic infection
E) nonmotile cells in connective tissue that promote inflammation
,

F) C) and D)
G) A) and B)

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Positive selection of lymphocytes refers to the


A) processing of an antigen by a macrophage.
B) proliferation of natural killer cells.
C) production of antigen-specific antibodies.
D) survival of pre-B and pre-T cells that are capable of an immune response.
E) replication of memory cells.

F) B) and D)
G) C) and D)

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Match the term with the appropriate description. -germinal centers


A) lipids that cause smooth muscle relaxation and vasodilation
B) lymph nodules aggregated in the small intestinal wall
C) rounded epithelial structures found in the medulla of thymus
D) areas of a lymph node where lymphocytes divide
E) a chemical released from mast cells that causes vasodilation

F) D) and E)
G) A) and D)

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MHC class II molecules are found on


A) neutrophils,monocytes,and macrophages.
B) dendritic cells,B cells,and helper T cells.
C) monocytes,helper T cells,and neutrophils.
D) B cells,macrophages,and dendritic cells.
E) B cells,C cells and D cells.

F) B) and D)
G) A) and B)

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Once cytotoxic T cells are produced,which of the following is (are) consistent with their ability to attack intracellular viruses?


A) Most nucleated cells process antigens through the MHC class I mechanisms.
B) Viral antigens are processed by the MHC class I mechanism and are presented to the cell surface.
C) Cytotoxic T cells bind to MHC class I processed antigens.
D) Cytotoxic T cells bound to the MHC class I processed antigens release lymphokines.
E) All of these choices are correct.

F) None of the above
G) C) and D)

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Cells that process antigen and present antigens to other immune cells are called


A) plasma cells.
B) antigen-presenting cells.
C) B receptor cells.
D) T suppressor cells.
E) antibodies.

F) C) and E)
G) A) and B)

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Match the appropriate characteristic with the type of immunity. -cells mature in thymus gland


A) innate immunity
B) antibody-mediated immunity
C) cell-mediated immunity
D) both antibody and cell-mediated immunity
E) innate immunity,antibody-mediated immunity and cell-mediated immunity

F) D) and E)
G) All of the above

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Which of the following most accurately describes how foreign substances can activate complement?


A) Antibodies can bind to foreign antigens and activate complement through the classical pathway.
B) Foreign substances can bind to spontaneously activated C3 and stabilize it.
C) Foreign proteins bind to C1 and activate it.
D) Foreign proteins are phagocytized by macrophages and directly activate complement.
E) Antibodies can bind to foreign antigens and activate complement through the classical pathway and foreign substances can bind to spontaneously activated C3 and stabilize it.

F) A) and C)
G) D) and E)

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The white pulp of the spleen


A) contains lymphocytes that can stimulate an immune response.
B) filters lymph as it flows through the spleen.
C) destroys defective red blood cells.
D) stimulates immune responses,filter lymph,and destroys defective red blood cells.

E) B) and C)
F) A) and C)

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Which of the following statements concerning neutrophils and macrophages is false?


A) They both exhibit chemotaxis.
B) They both move by amoeboid motion.
C) Both are capable of phagocytosis.
D) Both release histamine when activated.
E) Both can squeeze between cells.

F) A) and E)
G) B) and D)

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______ determines which B-cell is cloned in an antibody-mediated response.


A) The antibody
B) The antigen
C) A macrophage
D) Complement
E) A neutrophil

F) A) and D)
G) A) and C)

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Match the appropriate characteristic with the type of immunity. -origin of cells is red bone marrow


A) innate immunity
B) antibody-mediated immunity
C) cell-mediated immunity
D) both antibody and cell-mediated immunity
E) innate immunity,antibody-mediated immunity and cell-mediated immunity

F) B) and E)
G) B) and C)

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Lymphatic tissue contains an interlaced network of reticular fibers that functions to


A) produce lymphocytes.
B) produce capsules around lymph nodes.
C) attack microorganisms.
D) line the walls of lymphatic vessels.
E) trap microorganisms.

F) B) and C)
G) A) and E)

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Which of the following is NOT a secondary lymphatic organ?


A) spleen
B) lymph node
C) lymphatic nodule
D) thymus gland

E) B) and C)
F) All of the above

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Which of the following is NOT a function of the lymphatic system?


A) Defending from infection caused by microorganisms and other foreign substances.
B) Aiding in erythropoiesis of red blood cells.
C) Maintaining fluid balance by returning excess interstitial fluid to the blood.
D) Absorbing and transporting lipids from the digestive tract.

E) None of the above
F) B) and C)

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