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How many polypeptides would be present if the following was treated with trypsin? How many polypeptides would be present if the following was treated with trypsin?   A)  1 B)  2 C)  3 D)  4 E)  5


A) 1
B) 2
C) 3
D) 4
E) 5

F) A) and E)
G) A) and C)

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The organic portion of which of the following biological materials does not consist mainly of polypeptides and/or proteins?


A) Enzymes
B) Hair
C) Hemoglobin
D) Membranes
E) Insulin

F) A) and C)
G) B) and E)

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Which of the following amino acids is theoretically capable of existing in two diastereomeric forms?


A) Cysteine
B) Threonine
C) Leucine
D) Serine
E) Tryptophan

F) A) and D)
G) A) and B)

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Which of the following amino acids contains an aromatic ring?


A) Alanine
B) Serine
C) Tyrosine
D) Asparagine
E) Glycine

F) A) and E)
G) A) and C)

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Given that the pKa of the acidic form of proline is 2.0,and the pKa of the basic form of proline is 10.6,what is the isoelectric point?


A) 2.0
B) 6.3
C) 4.4
D) 10.6
E) 7.0

F) B) and D)
G) A) and B)

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In a DNA molecule,at which point would the base shown be attached to a deoxyribose fragment? In a DNA molecule,at which point would the base shown be attached to a deoxyribose fragment?   A)  1 B)  2 C)  3 D)  4 E)  5


A) 1
B) 2
C) 3
D) 4
E) 5

F) C) and D)
G) B) and C)

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The artificial sweetener aspartame is a derivative of the dipeptide asp-phe.If aspartame (asp-phe) was prepared from racemic amino acids,how many stereoisomers (diastereomers + enantiomers) could be formed? The artificial sweetener aspartame is a derivative of the dipeptide asp-phe.If aspartame (asp-phe) was prepared from racemic amino acids,how many stereoisomers (diastereomers + enantiomers) could be formed?   A)  2 B)  3 C)  4 D)  6 E)  8


A) 2
B) 3
C) 4
D) 6
E) 8

F) C) and D)
G) A) and C)

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How many amino acid residues are present in the following polypeptide? How many amino acid residues are present in the following polypeptide?   A)  4 B)  5 C)  6 D)  7 E)  8


A) 4
B) 5
C) 6
D) 7
E) 8

F) A) and E)
G) B) and D)

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Which of the following DNA base pairs can participate in Watson and Crick type hydrogen bonding?


A) A-T
B) G-T
C) G-C
D) Both A and B
E) Both A and C

F) B) and D)
G) A) and B)

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At the isoelectric point,the amino acid alanine will exist as what structure?


A) A positive ion
B) A negative ion
C) An uncharged molecule
D) A zwitterion
E) A carbocation

F) All of the above
G) A) and D)

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The difference(s) between DNA and RNA is (are) :


A) DNA incorporates 2-deoxyribose sugars rather than ribose.
B) RNA is smaller than DNA.
C) DNA uses thymine,RNA uses uracil.
D) Two of the above are true.
E) All of the above are true.

F) C) and E)
G) A) and C)

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Disulfide bonds in proteins


A) result from oxidation of thiols (RSH) .
B) function to help maintain the shape of proteins.
C) can be broken by reduction reactions.
D) link two cysteine amino acid residues.
E) All of these are true.

F) None of the above
G) C) and D)

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How many tripeptides containing one residue each of L-alanine,L-valine,and glycine are possible?


A) 2
B) 3
C) 4
D) 6
E) 9

F) B) and C)
G) All of the above

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The primary structure of a protein refers to the


A) sequence of amino acids.
B) overall 3-dimensional shape.
C) localized shape of the backbone.
D) degree of aggregation with other proteins.
E) structure of the active site.

F) None of the above
G) C) and D)

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Which of the following statements is not true of amino acids?


A) They are less acidic than carboxylic acids.
B) In acid solution (pH ~ 2) they would show an IR absorption near 1720 cm-1.
C) They are soluble in water but not in non-polar organic solvents.
D) They are more basic than amines.
E) In basic solution (pH ~ 12) they would show an IR absorption near 3300 cm-1.

F) A) and B)
G) B) and C)

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Which nitrogen in the imidazole ring of histidine is the more basic? Which nitrogen in the imidazole ring of histidine is the more basic?   A)  #1 B)  #2 C)  both have same basicity D)  neither is basic E)  the histidine N-H is actually acidic


A) #1
B) #2
C) both have same basicity
D) neither is basic
E) the histidine N-H is actually acidic

F) A) and B)
G) All of the above

Correct Answer

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Which amino acid is shown? Which amino acid is shown?   A)  Alanine B)  Glycine C)  Tyrosine D)  Lysine E)  Arginine


A) Alanine
B) Glycine
C) Tyrosine
D) Lysine
E) Arginine

F) All of the above
G) A) and C)

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What material can be used repetitively (on a given sample) to sequence a polypeptide from the N-terminal end?


A) Chymotrypsin
B) Sanger reagent
C) Trypsin
D) Edman reagent
E) Carboxypeptidase

F) B) and C)
G) D) and E)

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Which of the following amino acids would have the highest isoelectric point?


A) Lysine
B) Glutamine
C) Aspartic acid
D) Alanine
E) Tryptophan

F) None of the above
G) A) and C)

Correct Answer

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